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Platelet transfusion after stroke not beneficial for patients using antiplatelet drugs

Platelet transfusion after stroke not beneficial for patients using antiplatelet drugs

The common practise of giving patients with an acute intracerebral haemorrhage a platelet transfusion is not effective and might even be dangerous. That is the conclusion of a paper by an international group of researchers that was published in The Lancet. They specifically studied patients that were on antiplatelet drugs prior to having the bleeding. Continue reading

‘Milestone’ in cocaine dependence treatment: dexamfetamine effective and safe

‘Milestone’ in cocaine dependence treatment: dexamfetamine effective and safe

Heroin-dependent patients who are also struggling with cocaine dependence can be successfully treated for this second addiction using sustained-release dexamfetamine. That is written by Dutch investigators in The Lancet. In an accompanying comment, Swiss psychiatrists call these results a milestone. Continue reading

Personalised medicine not yet validated for cancer

Personalised medicine not yet validated for cancer

In theory, the prescription of medication compensating the deregulation of molecular pathways should lead to better treatment of cancer. However, in a multicentre phase II study in France, this approach did not render longer periods of progression-free survival. The results, published in The Lancet, raise concerns about the implementation of personalised medicine in cancer. Continue reading

Evidence against predicted dementia epidemic

Evidence against predicted dementia epidemic

Because of the ageing of the general population and an increase in dementia patients, dementia was predicted to become a true epidemic. However, this assumption is based on data from twenty years ago. A review in The Lancet of recent epidemiologic publications concerning dementia epidemiology contradicts the conclusions previously made. Continue reading

Cystic fibrosis gene therapy has little effect

Cystic fibrosis gene therapy has little effect

Since the discovery of the mutated CFTR gene in cystic fibrosis patients, scientists have been working on the development of gene therapy for this patient group. Recently, a gene therapy phase II clinical trial with 116 participants in the UK resulted in the halt of disease progression, although there was little effect. The article was published in The Lancet. Continue reading

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